![]() ![]() The chimeric antigen receptor is then added to immune. This research was conducted at the Tucker Davis Research Facility at Rockefeller University, led by Dr. Chimera Drosophila Termination biology cell chromosome development embryo fertilization gene expression genes genetics information mammals. A special receptor created in the laboratory that is designed to bind to certain proteins on cancer cells. This research ultimately resulted in game-changing discovery of a unique genetic mutation, a chimeric gene, common to all fibrolamellar tissues studied. Identification of mutations common in FLC tumors is critical to enhancing the understanding of the underlying biology of this tumor and allow for development of novel therapeutics. The team used whole genome sequencing together with RNA sequencing to identify mutations in FLC tumors compared to their normal liver counterparts. The goal of this project was to identify genetic mutations present in FLC. A tetragametic chimera can have two genetic profiles in their blood, and distinct DNA markers in different parts of their body (11). Principal Investigator: Sandy Simon, Ph.D., Professor, Rockefeller University ![]()
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